Study of the Histological Effects of Frying Fodder with Olive Oil, Bay Leaf, and Ginger Root on the Heart of Healthy Mice

Muhanad Hamed Salih  Saeed; Fatema A.  Mahamed; Abdulmunem Kurdi  Abdullah

Muhanad Hamed Salih Saeed Department of Science, College of Basic Education, Sharqat, Tikrit University, Iraq
Fatema A. Mahamed Department of Science, College of Basic Education, Sharqat, Tikrit University, Iraq
Abdulmunem Kurdi Abdullah Department of Science, College of Basic Education, Sharqat, Tikrit University, Iraq

Keywords: heart, ginger root, bay leaves, fried olive oil

Abstract

The research was conducted to investigate the effect of virgin olive oil on heart tissue, the effect of adding bay leaves and ginger roots separately, and to evaluate the possible tissue effects of damage and treatment. The study included (20) male and female mice that were subjected to the necessary laboratory conditions for 30 days. It was divided as follows: a control group; A group for frying its fodder in olive oil; A group that fried its feed in olive oil with ginger roots and a group that fried its feed in olive oil with bay leaves. The results of the group whose feed was fried in olive oil showed the occurrence of congestion and hemolysis, in addition to the presence of degeneration and disintegration of the cardiac muscle fibres and bleeding between the muscle fibres. Dense infiltration of inflammatory cells was also observed, while there was a significant improvement in the group whose feed was fried in olive oil with bay leaves. Muscle fibres appeared normally and there was no improvement in the group whose feed was fried in olive oil with ginger roots compared to the group whose feed was fried in olive oil alone. Our study concluded that the use of olive oil in the frying process has harmful histological effects on the heart, and the use of bay leaves during the frying process can have a significant therapeutic effect on the histological structure of the heart, while the use of ginger roots does not have any therapeutic effect on the histological structure of the heart against toxicity. Induced by the frying process of olive oil.

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References

K. Bernhard and E. Scheitlin, “Absorption of mineral oils.,” 1952.

A. C. Sánchez-Gimeno, A. I. Negueruela, M. Benito, A. Vercet, and R. Oria, “Some physical changes in Bajo Aragón extra virgin olive oil during the frying process,” Food Chem., vol. 110, no. 3, pp. 654–658, 2008.

A. Chiou and N. Kalogeropoulos, “Virgin olive oil as frying oil,” Compr. Rev. Food Sci. Food Saf., vol. 16, no. 4, pp. 632–646, 2017.

D. E. Schraufnagel, “The health effects of ultrafine particles,” Exp. Mol. Med., vol. 52, no. 3, pp. 311–317, 2020.

M. Vaisey-Genser, L. J. Malcomson, R. Przybylski, and N. A. M. Eskin, “Consumer acceptance of stored canola oils in canola. 12th Project report research on canola, seed, oil meal,” Canada Canola Counc. Canada, pp. 189–202, 1999.

V. Messina, A. Biolatto, A. Descalzo, A. Sancho, R. Baby, and N. W. De Reca, “Effect of pan‐frying in extra‐virgin olive oil on odour profile, volatile compounds and vitamins,” Int. J. food Sci. Technol., vol. 44, no. 3, pp. 552–559, 2009.

K. S. Woo et al., “The impact of particulate matter air pollution (PM2. 5) on atherosclerosis in modernizing China: a report from the CATHAY study,” Int. J. Epidemiol., vol. 50, no. 2, pp. 578–588, 2021.

C. Nutakor, J. A. Essiedu, P. Adadi, and O. N. Kanwugu, “Ginger beer: An overview of health benefits and recent developments,” Fermentation, vol. 6, no. 4, p. 102, 2020.

S. Batool, R. A. Khera, M. A. Hanif, and M. A. Ayub, “Bay leaf,” in medicinal plants of South Asia, Elsevier, 2020, pp. 63–74.

L. G. Luna, “Manual of histologic staining methods of the Armed Forces Institute of Pathology,” in Manual of histologic staining methods of the Armed Forces Institute of Pathology, 1968, pp. xii–258.

Y.-S. Lin, D.-L. Chen, H.-M. Shaw, G.-J. Wang, and P.-M. Chao, “Consuming oxidative frying oil impairs cardiac energy production and calcium recycling, causing cardiac hypertrophy, fibrosis and diastolic dysfunction in male Sprague Dawley rats,” J. Nutr. Biochem., vol. 98, p. 108816, 2021.

A. Patsioura, A. M. Ziaiifar, P. Smith, A. Menzel, and O. Vitrac, “Effects of oxygenation and process conditions on thermo-oxidation of oil during deep-frying,” Food Bioprod. Process., vol. 101, pp. 84–99, 2017.

R. P. Venkata and R. Subramanyam, “Evaluation of the deleterious health effects of consumption of repeatedly heated vegetable oil,” Toxicol. reports, vol. 3, pp. 636–643, 2016.

K. Ganesan, K. Sukalingam, and B. Xu, “Impact of consumption and cooking manners of vegetable oils on cardiovascular diseases-A critical review,” Trends Food Sci. Technol., vol. 71, pp. 132–154, 2018.

H. Amsalu, T. Wondimnew, T. Mateos, M. Fekadie, and G. Bogale, “The effect of palm oil‐fried street kokor on liver and kidney biomarkers of Swiss albino mice,” J. Lipids, vol. 2020, no. 1, p. 8819749, 2020.

M. González-Rodríguez et al., “Oleocanthal, an antioxidant phenolic compound in extra virgin olive oil (EVOO): a comprehensive systematic review of its potential in inflammation and Cancer,” Antioxidants, vol. 12, no. 12, p. 2112, 2023.

M. J. Saleh and K. A. Al-Badrany, “Preparation, Characterization of New 2-Oxo Pyran Derivatives by AL2O3-OK Solid Base Catalyst and Biological Activity Evaluation,” Cent. Asian J. Med. Nat. Sci., vol. 4, no. 4, pp. 222–230, 2023.

A. W. A. S. Talluh, “Preparation, Characterization, Evaluation of Biological Activity, and Study of Molecular Docking of Azetidine Derivatives,” Cent. Asian J. Med. Nat. Sci., vol. 5, no. 1, pp. 608–616, 2024.

A. Talluh, J. N. Saleh, and M. J. Saleh, “Preparation, Characterization and Evaluation of Biological Activity and Study of Molecular Docking of Some New Thiazoli-dine Derivatives,” 2024.

A. W. A. S. Talluh, M. J. Saleh, J. N. Saleh, K. Al-Badrany, and H. mohammed saleh Al-Jubori, “Preparation, characterization, and evaluation of the biological activity of new 2, 3-dihydroquinazoline-4-one derivatives,” Eur. J. Mod. Med. Pract., vol. 4, no. 4, pp. 326–332, 2024.

J. N. Saleh and A. Khalid, “Synthesis, Characterization and Biological Activity Evaluation of Some New Pyrimidine Derivatives by Solid Base Catalyst AL2O3-OBa,” Cent. Asian J. Med. Nat. Sci., vol. 4, no. 4, pp. 231–239, 2023.

Y. M. Ahmed and R. Z. Sulaiman, (2018). Detection some active Compounds in the Leaves and Stems of Local Coriander Plant-Coriandrum sativum L. Tikrit Journal of Pure Science, 23(3), 6-15.‏