Physiological Study Of The Effect Of Codeine Addiction By Dosing Different Concentrations On Testosterone Levels In Male Albino Rats

Marwa Ahmed Meri; Hawraa Ayad; Amjed Mohammed Sahib

doi:10.51699/cajotas.v6i3.1587

Marwa Ahmed Meri Directorate of Education in AL-Najaf, Ministry of Education, AL-Najaf, Iraq
Hawraa Ayad Directorate of Education in AL-Najaf, Ministry of Education, AL-Najaf, Iraq
Amjed Mohammed Sahib Directorate of Education in AL-Najaf, Ministry of Education, AL-Najaf, Iraq

DOI: https://doi.org/10.51699/cajotas.v6i3.1587

Keywords: codeine, testosterone, FSH, LH

Abstract

This study aimed to evaluate the effect of codeine on testosterone levels in male albino rats. Thirty male rats were divided into three groups: a control group (which did not receive codeine) and two experimental groups (which received different doses of codeine). The doses were administered daily for 8 weeks, and blood testosterone levels were measured using ELISA. The results showed a significant decrease in testosterone levels in the groups receiving codeine, with a greater decrease in the group This study aimed to evaluate the effect of different doses of codeine on body weight testosterone levels in male albino rats, and to determine whether this effect is dose dependent.receiving the high dose. These results suggest that codeine may negatively affect hormonal function in males, calling for further studies to understand the exact mechanism of this effect.

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